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4.
J Am Vet Med Assoc ; 216(12): 1904-10, 2000 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-10863585
10.
J Am Vet Med Assoc ; 188(12): 1426-31, 1986 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-3528096

RESUMO

Posthypoglycemic hyperglycemia (rebound hyperglycemia) after overdosing of insulin was diagnosed in 6 cats with diabetes mellitus. Administration of excessive insulin induced hypoglycemia within 4 to 8 hours, followed by rebound hyperglycemia. Diagnosis was made by serial blood glucose determinations during a 20- to 24-hour period after insulin administration. Four cats had a history of difficulty in regulating the diabetic state. In 2 cats, rebound hyperglycemia was diagnosed on routine serial blood glucose determinations. All of the cats were hyperglycemic for most of the day. Rebound hyperglycemia was observed with both intermediate (neutral protamine hagedorn) and long-acting (protamine zinc iletin) insulins, and the range of insulin doses at which the disorder developed overlapped previously determined therapeutic doses for these insulins in the cat. Urine glucose and single afternoon blood glucose determinations were inadequate and potentially misleading in monitoring diabetic cats receiving excessive amounts of insulin.


Assuntos
Doenças do Gato/tratamento farmacológico , Diabetes Mellitus/veterinária , Hiperglicemia/veterinária , Insulina/efeitos adversos , Animais , Gatos , Diabetes Mellitus/tratamento farmacológico , Feminino , Hiperglicemia/induzido quimicamente , Insulina/uso terapêutico , Masculino
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